Workshop on Polymers with spatial and mechanical constraints 7 - 9 luglio Istituto Veneto di Scienze, Lettere ed Arti Palazzo Franchetti

Il Workshop è organizzato dal Dipartimento di Fisica ed Astronomia dell'Università di Padova e dalla Scuola Internazionale Superiore di Studi Avanzati di Trieste in collaborazione con l 'Istituto Veneto di Scienze, Lettere ed Arti

Scientific background The configurations and function of large biological molecules such as DNA and RNA can be nowadays manipulated either through confinement in nano-fluidic volumes or by applying pico-forces by using optical/magnetic tweezers and atomic-force microscopes. These very recent techniques obviate the need for cloning and molecular amplification steps and enable researchers to detect physical phenomena that in the past would have been obscured by ensemble averaging. These devices can be used not only to study the dynamical and mechanical properties of biomolecules but also to obtain genomic information and to characterise biological interactions at molecular level.These phenomena will be addressed by this workshop, spanning from application of these devices in the generic science to the exploration of the underlying physics. The workshop, by gathering eminent researchers in nano-fluidics, biophysics, material physics and computational physics (see list below) will integrate state of the art micro-manipulation single molecule experiments, theory and computational approaches.

Organizers Cristian Micheletti Affiliation: SISSA, Trieste Enzo Orlandini Affiliation: Dipartimento di Fisica, Università di Padova and Sezione INFN Padova Attilio L. Stella Affiliation: Dipartimento di Fisica, Università di Padova and Sezione INFN Padova