The Candidacy of the “Tre Venezie” to European Capital of Culture Event for 2019 places a detail challenge to the city. It, in fact, finds itself to being the place with higher visibility inside a macro-region, that, with the Candidacy, tries to assert own identity also on international scale. The various vocations and the missions chosen from the territories of the Northeast compose a complex picture, in which Venice, with its cultural happens and the force of its visibility, is destined to play a symbolic and substantial role. How to interpret this role in the Candidacy to European Capital of Culture Event? The convention tries to offer some answers putting in field the Knowledge of Ca'Foscari University.